(Bloomberg) -- New outbreaks in the U.S. have raised concerns about the pace of reopening the economy. Singapore prepared to ease curbs, while the World Health Organization said a cluster of cases in Beijing is a concern.

U.S. regulators revoked emergency-use authorization for two malaria drugs touted by President Donald Trump as a Covid-19 treatment after determining they were unlikely to work and could be dangerous. Scientists found that one in five people worldwide are at risk for a severe illness if they contract the virus.

The Oscar and Bafta film awards were delayed until April after the virus pushed back movie releases. JPMorgan Chase & Co. will start returning more traders to its New York office next week.

Key Developments:

  • Virus Tracker: Cases pass 7.9 million; deaths exceed 434,000
  • U.S. cases continue to rise, undermining reopening push
  • Shoppers in England return to stores for first time since March
  • Second U.K. vaccine to begin human testing
  • Shortage of safety supplies adds to U.S. reopening risks
  • New York’s Chinatown is starting over, and it’s painful

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One in Five People Seen at Risk of Severe Covid (6:47 a.m. HK)

One in five people worldwide have an underlying health condition that puts them at risk for a severe Covid-19 illness if they contract the virus, scientists found.

An estimated 1.7 billion people suffer from conditions ranging from type 2 diabetes to heart disease, according to a study published in The Lancet Global Health. About 349 million of them would probably need to go to the hospital for treatment if they were infected, Andrew Clark, an associate professor at the London School of Hygiene and Tropical Medicine, and colleagues found.

The researchers took risk factors highlighted in official guidelines, including heart disease and diabetes, and used broad epidemiology data such as the Global Burden of Diseases study to arrive at their estimates. Not everyone with an underlying condition would go on to develop severe symptoms, they said.

Texas Hospitalizations at Record; New Cases Slow (6 a.m. HK)

Texas set its fourth-consecutive record for people hospitalized with the virus, with the number rising to 2,326. New cases of the virus jumped by 1,254 to 89,108, the lowest increase in a week.

Tension between the state’s major cities and the governor’s office continues to grow as the outbreak gains momentum and local officials strive to slow down the reopening schedule pushed by Governor Greg Abbott. Houston Mayor Sylvester Turner announced there would be no public Fourth of July celebration. Instead, the city will hold a virtual symphony concert, and a 15-minute fireworks display near the city center.

“This was an easy decision, as the safety of Houstonians is our greatest concern and the numbers of people testing positive continues to increase every day,” Turner said.

Miami-Area Mayors Won’t Restart Lockdowns (5:45 p.m. NY)

Miami-Dade County Mayor Carlos Gimenez said he was watching indicators of a recent uptick in cases, but he doesn’t plan to reinstate lockdowns or otherwise roll back reopenings of Florida’s biggest county.

His remarks follow those made earlier Monday by the Miami and Miami Beach mayors who also aren’t planning to reverse their reopenings. Both cities are in Gimenez’s county.

“I always have concerns about Covid-19, never know what this virus is going to do,” Gimenez said. “I’m just not -- we’re not ready to say that we’re going to be closing down our economy. That’s the last thing I want to do.”

Second U.K. Vaccine to Begin Human Testing (5 p.m. NY)

A second experimental Covid-19 vaccine from the U.K. is starting tests in humans this week, relying on cutting-edge technology that scientists hope will allow hundreds of millions of doses to be produced quickly.

Imperial College London’s vaccine is backed by 41 million pounds ($52 million) in U.K. funding along with another 5 million pounds of donations, including contributions from the public, the government said on Monday. The work is based on technology called self-amplifying RNA. If the vaccine yields a promising immune response, larger trials would begin later in the year with about 6,000 volunteers.

California Governor Says Trends Remain Stable (4:50 p.m. NY)

As confirmed infections continue to climb in California, the hospitalization, ICU and positive test rates remain stable, suggesting that reopenings can proceed even as the state is “by no stretch of the imagination out of the woods,” Governor Gavin Newsom said at a press briefing.

“There was some sense that the hospitalization numbers would begin to increase,” Newsom said, discussing the increased socialization upon the state’s initial reopening on May 8 and Memorial Day weekend. “The trend line remains remarkably stable.”

Newsom emphasized that the ultimate decisions about reopening should be made at the local level because the severity of the pandemic varies across the state. California is currently assisting 13 of the state’s 58 counties with “targeted engagement,” providing additional resources to those that are seeing concerning data points.

San Francisco, which has had some of the state’s tightest restrictions, said Monday it would initiate another phase of its reopening, allowing indoor retail with restrictions for malls, small outdoor gatherings and professional sports with no in-person spectators.

U.S. Cases Rise 0.9% (4 p.m. NY)

Coronavirus cases in the U.S. increased by 19,244 from the same time Sunday to 2.1 million, according to data collected by Johns Hopkins University and Bloomberg News. The 0.9% increase was lower than the average daily increase of 1.1% over past seven days. Deaths rose 0.3% to 115,896.

  • Cases in Arizona, where concern is rising about a new wave, rose 2.8% to 36,719, according to the Johns Hopkins and Bloomberg News data.
  • Florida reported 77,326 cases, up 2.3% from a day earlier, compared with an average increase of 2.4% in the previous seven days. Deaths reached 2,938, an increase of 0.2%.
  • New Jersey’s death toll rose by 52 to 12,676, while new cases increased by 274 to 167,103, a 0.1% rise that was less than the 0.2% increase of the prior seven-day average.
  • California cases rose 1.7% to 151,452, compared with an average increase of 2.1% in the past seven days, according to the state’s website. Deaths rose 0.5% to 5,089.
  • Texas cases climbed 1.4%, less than the seven-day average of a 2.3% increase.

Toronto Under Lockdown as Ontario Reopens (4 p.m. NY)

Canada’s financial capital will remain under partial lockdown as Ontario gradually reopens other regions of its province after months of Covid-19 restrictions.

Niagara and Hamilton are among areas that will be allowed to reopen businesses ranging from hair salons to shopping malls, swimming pools and outdoor dining on patios as of Friday, Premier Doug Ford said Monday.

With new infections still too high, Toronto, Peel and the city of Windsor, just across the border from Detroit, are not part of the second phase in the province’s three-stage restart.

Ten Nations Account for Most New Cases: WHO (1 p.m. NY)

In the past two weeks, countries have reported more than 100,000 new cases almost every day, and 75% are coming from 10 countries, mostly in the Americas and South Asia, Tedros Adhanom Ghebreyesus, the head of the World Health Organization, said at a briefing in Geneva. That means every day there’s more cases reported than during the first two months of the outbreak. There are many hot spots in Latin America, and cases are also increasing in Africa, the Mideast and Central Europe.

A cluster of cases in Beijing is a concern because the city had gone 50 days without reporting any infections, said Mike Ryan, head of the WHO’s health emergencies program. The WHO expects China to share genome sequencing data on that outbreak soon, as it has with other data, Ryan said. Covid-19 technical leader Maria Van Kerkhove said she is making a plea for all countries to share more genome sequence data.

N.Y. Cases Declining as State Reopens (12:44 p.m. NY)

New York Governor Andrew Cuomo Monday called on local governments to enforce social-distancing guidelines as the state reopens. If numbers start to go up again in certain areas of the state, those regions will have to take a step back, he said at his daily briefing.

New York, which at one point had the highest number of cases per capita in the nation, now is concerned about people from other states that have a high rate of increase traveling to the Empire State, he said. Early in the outbreak, some states tried to bar visitors from New York.

“Talk about a great irony,” Cuomo said.

Hospitalizations in the state declined by nearly 50 to 1,608 as of Sunday, and there were 25 virus-related fatalities on Sunday, according to state data. At one point, the daily number of deaths was almost 800.

The state is adjusting reopening guidelines, allowing regions in phase 3 to have gatherings of up to 25 people instead of just 10, because the number of positive cases remains so low, Cuomo said. Western New York will start phase three of reopening on Tuesday, and the capital region will do so on Wednesday.

FDA Pulls Authorization for Trump-Touted Drug (11:46 a.m. NY)

U.S. regulators revoked emergency-use authorization for two malaria drugs touted by President Donald Trump as a Covid-19 treatment after determining they were unlikely to work against the virus and could have dangerous side effects.

The Food and Drug Administration said Monday that chloroquine and hydroxychloroquine “are unlikely to be effective in treating Covid-19.”

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